format-version: 1.2 data-version: releases/2020-03-10 date: 03:05:2013 17:41 saved-by: fbb subsetdef: granular_stage "Subset consisting of classes describing highly granular developmental stages (for instance, '23-year-old'). Such stages might be useful for annotation purpose, but might be folded into less granular parents for display purpose." default-namespace: mouse_stages_ontology ontology: mmusdv [Term] id: MmusDv:0000000 name: mouse life cycle stage def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [UBERON:0000105] synonym: "developmental stage" EXACT [] synonym: "stage" NARROW [] xref: UBERON:0000105 [Term] id: MmusDv:0000001 name: mouse life cycle namespace: mouse_developmental_stage def: "Temporal interval that defines mouse life from prenatal stage until late adult stage." [Bgee:curator] xref: UBERON:0000104 is_a: MmusDv:0000000 ! mouse life cycle stage property_value: start_dpc "0.45" xsd:float [Term] id: MmusDv:0000002 name: embryonic mouse stage namespace: mouse_developmental_stage def: "Prenatal stage that starts with fertilization and ends with a fully formed embryo, before undergoing last development during the fetal stage." [Bgee:curator] comment: By embryo we mean in the sense of up to the 2nd week postfertilization (beginning of Theiler stage 23), we treat fetus as a separate stage. is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000042 ! prenatal stage property_value: start_dpc "0.45" xsd:float property_value: start_dpf "0.0" xsd:float [Term] id: MmusDv:0000003 name: Theiler stage 01 namespace: mouse_developmental_stage def: "Embryonic stage defined by a one-cell embryo (fertilised egg) with zona pellucida present." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_1] comment: "Starts the mouse development sequence, range from embryonic age 0-0.9 dpc (day post coitum). Assumes that fertilization takes place around midnight during a 7pm to 5am dark cycle. Noon of the day on which the vaginal plug is found the embryos are aged 0.5 d.p.c (days post coitum)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy "adapted from"] synonym: "E0-2.5" EXACT [] synonym: "Theiler stage 1" EXACT [] synonym: "TS01 (E0-2.5)" RELATED [EMAPA:TS01] synonym: "zygote stage" RELATED [] xref: EMAPA:TS01 xref: UBERON:0000106 xref: XUO:0000045 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000002 ! embryonic mouse stage property_value: start_dpc "0.45" xsd:float [Term] id: MmusDv:0000004 name: cleavage stage namespace: mouse_developmental_stage def: "Embryonic stage consisting of division of cells in the early embryo." [UBERON:0000107] comment: The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. xref: UBERON:0000107 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000002 ! embryonic mouse stage [Term] id: MmusDv:0000005 name: Theiler stage 02 namespace: mouse_developmental_stage def: "Embryonic cleavage stage defined by a dividing 2-4 cells egg." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_2] comment: Embryonic age 1 dpc (day post coitum). synonym: "E1-2.5" EXACT [] synonym: "Theiler stage 2" EXACT [] synonym: "TS02" EXACT [] synonym: "TS02 (E1-2.5)" RELATED [EMAPA:TS02] xref: EMAPA:TS02 xref: XUO:0000046 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000003 ! Theiler stage 01 relationship: part_of MmusDv:0000004 ! cleavage stage property_value: start_dpc "1.0" xsd:float [Term] id: MmusDv:0000006 name: Theiler stage 03 namespace: mouse_developmental_stage def: "Embryonic cleavage stage defined by a dividing 4-16 cells egg, early to fully compacted morula." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_3] comment: Embryonic age 2 dpc (day post coitum). synonym: "E1-3.5" EXACT [] synonym: "Theiler stage 3" EXACT [] synonym: "TS03" EXACT [] synonym: "TS03 (E1-3.5)" RELATED [EMAPA:TS03] xref: EMAPA:TS03 xref: XUO:0000047 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000005 ! Theiler stage 02 relationship: part_of MmusDv:0000004 ! cleavage stage property_value: start_dpc "2.0" xsd:float [Term] id: MmusDv:0000007 name: blastula stage namespace: mouse_developmental_stage def: "Embryonic stage that is an early stage of embryonic development in animals and is produced by cleavage of a fertilized ovum, with formation of a central fluid-filled cavity called the blastocoel." [UBERON:0000108] comment: The blastula follows the morula and precedes the gastrula in the developmental sequence. is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000002 ! embryonic mouse stage [Term] id: MmusDv:0000008 name: Theiler stage 04 namespace: mouse_developmental_stage def: "Embryonic blastula stage defined by a dividing 16-40 cells egg, with early evidence of the blastocoelic cavity." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_4] comment: Embryonic age 3 dpc (day post coitum). synonym: "E2-4" EXACT [] synonym: "Theiler stage 4" EXACT [] synonym: "TS04" EXACT [] synonym: "TS04 (E2-4)" RELATED [EMAPA:TS04] xref: EMAPA:TS04 xref: XUO:0000048 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000006 ! Theiler stage 03 relationship: part_of MmusDv:0000007 ! blastula stage property_value: start_dpc "3.0" xsd:float [Term] id: MmusDv:0000009 name: Theiler stage 05 namespace: mouse_developmental_stage def: "Embryonic blastula stage defined by a zona free blastocyst (zona pellucida absent)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_5] comment: Embryonic age 4 dpc (day post coitum). synonym: "E3-5.5" EXACT [] synonym: "Theiler stage 5" EXACT [] synonym: "TS05" EXACT [] synonym: "TS05 (E3-5.5)" RELATED [EMAPA:TS05] xref: EMAPA:TS05 xref: XUO:0000049 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000008 ! Theiler stage 04 relationship: part_of MmusDv:0000007 ! blastula stage property_value: has_stage_marker GO:0001835 property_value: start_dpc "4.0" xsd:float [Term] id: MmusDv:0000010 name: Theiler stage 06 namespace: mouse_developmental_stage def: "Embryonic blastula stage during which the blastocyst attaches, with first evidence of embryonic endoderm cells covering the blastocoelic surface of the inner cell mass." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_6] comment: Embryonic age 4.5 dpc (day post coitum). Refers to human CarnegieStage04. synonym: "E4-5.5" EXACT [] synonym: "Theiler stage 6" EXACT [] synonym: "TS06" EXACT [] synonym: "TS06 (E4-5.5)" RELATED [EMAPA:TS06] xref: EMAPA:TS06 xref: XUO:0000050 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000009 ! Theiler stage 05 relationship: part_of MmusDv:0000007 ! blastula stage property_value: start_dpc "4.5" xsd:float [Term] id: MmusDv:0000011 name: Theiler stage 07 namespace: mouse_developmental_stage def: "Embryonic blastula stage defined by implantation and formation of the egg cylinder resulting from the rapid increase in the number of inner cell mass cells." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_7] comment: Embryonic age 5 dpc (day post coitum). Refers to human CarnegieStage05. synonym: "E4.5-6" EXACT [] synonym: "Theiler stage 7" EXACT [] synonym: "TS07" EXACT [] synonym: "TS07 (E4.5-6)" RELATED [EMAPA:TS07] xref: EMAPA:TS07 xref: XUO:0000051 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000010 ! Theiler stage 06 relationship: part_of MmusDv:0000007 ! blastula stage property_value: has_stage_marker GO:0007566 property_value: start_dpc "5.0" xsd:float [Term] id: MmusDv:0000012 name: Theiler stage 08 namespace: mouse_developmental_stage def: "Embryonic blastula stage during which the egg cylinder differentiates into embryonic and extra-embryonic regions, and the pro-amniotic cavity appears." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_8] comment: Embryonic age 6 dpc (day post coitum). Refers to human CarnegieStage05. synonym: "E5-6.5" EXACT [] synonym: "Theiler stage 8" EXACT [] synonym: "TS08" EXACT [] synonym: "TS08 (E5-6.5)" RELATED [EMAPA:TS08] xref: EMAPA:TS08 xref: XUO:0000052 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000011 ! Theiler stage 07 relationship: part_of MmusDv:0000007 ! blastula stage property_value: start_dpc "6.0" xsd:float [Term] id: MmusDv:0000013 name: gastrula stage namespace: mouse_developmental_stage def: "Embryonic stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage." [UBERON:0000109] xref: UBERON:0000109 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000002 ! embryonic mouse stage [Term] id: MmusDv:0000014 name: Theiler stage 09 namespace: mouse_developmental_stage def: "Embryonic gastrula stage during which gastrulation starts with first evidence of mesoderm and visible embryonic axis." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_9] comment: Embryonic age 6.5 dpc (day post coitum). synonym: "E6.25-7.25" EXACT [] synonym: "Theiler stage 9" EXACT [] synonym: "TS09" EXACT [] synonym: "TS09 (E6.25-7.25)" RELATED [EMAPA:TS09] xref: EMAPA:TS09 xref: XUO:0000053 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000012 ! Theiler stage 08 relationship: part_of MmusDv:0000013 ! gastrula stage property_value: has_stage_marker UBERON:0000926 property_value: start_dpc "6.5" xsd:float [Term] id: MmusDv:0000015 name: Theiler stage 10 namespace: mouse_developmental_stage def: "Embryonic gastrula stage during which the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold; the exocoelom appears; the allantoic bud first appears, gastrulation continues and the node becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10] comment: Embryonic age 7 dpc (day post coitum), (range 6.5-7.5 dpc). Refers to human CarnegieStage08. synonym: "E6.5-7.75" EXACT [] synonym: "TS10" EXACT [] synonym: "TS10 (E6.5-7.75)" RELATED [EMAPA:TS10] xref: EMAPA:TS10 xref: XUO:0000054 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000014 ! Theiler stage 09 relationship: part_of MmusDv:0000013 ! gastrula stage property_value: has_stage_marker UBERON:0003888 property_value: has_stage_marker UBERON:0004340 property_value: has_stage_marker UBERON:0005971 property_value: start_dpc "7.0" xsd:float [Term] id: MmusDv:0000016 name: neurula stage namespace: mouse_developmental_stage def: "Embryonic stage defined by formation of a tube from the flat layer of ectodermal cells known as the neural plate." [UBERON:0000110] comment: This term was obsoleted as it was the only child associated to MmusDv:0000017., This stage starts the emergence of the central nervous system at embryonic age 7.5 dpc (day post coitum). synonym: "TheilerStage11" RELATED [] is_obsolete: true consider: MmusDv:0000017 [Term] id: MmusDv:0000017 name: Theiler stage 11 namespace: mouse_developmental_stage def: "Embryonic stage called presomite stage and defined by the formation of the neural plate." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11] comment: This stage starts the emergence of the central nervous system at embryonic age 7.5 dpc (day post coitum). synonym: "E7.25-8" EXACT [] synonym: "neurula stage" RELATED [] synonym: "TS11" EXACT [] synonym: "TS11 (E7.25-8)" RELATED [EMAPA:TS11] xref: EMAPA:TS11 xref: UBERON:0000110 xref: XUO:0000055 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000015 ! Theiler stage 10 relationship: part_of MmusDv:0000002 ! embryonic mouse stage property_value: has_stage_marker UBERON:0003075 property_value: start_dpc "7.5" xsd:float [Term] id: MmusDv:0000018 name: organogenesis stage namespace: mouse_developmental_stage def: "Embryonic stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [UBERON:0000111] xref: UBERON:0000111 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000095 ! Theiler stage 11d relationship: part_of MmusDv:0000002 ! embryonic mouse stage [Term] id: MmusDv:0000019 name: Theiler stage 12 namespace: mouse_developmental_stage def: "Organogenesis stage during which first somites become visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12] comment: Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09. synonym: "E7.5-8.75" EXACT [] synonym: "TS12" EXACT [] synonym: "TS12 (E7.5-8.75)" RELATED [EMAPA:TS12] xref: EMAPA:TS12 xref: XUO:0000056 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000017 ! Theiler stage 11 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker EMAPA:16173 property_value: start_dpc "8.0" xsd:float [Term] id: MmusDv:0000020 name: Theiler stage 13 namespace: mouse_developmental_stage def: "Organogenesis stage defined by the turning of the embryo; initiated in embryos with 6-8 pairs of somites and usually completed in embryos with 14-16 pairs of somites." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_13] comment: Embryonic age 8.5 dpc (day post coitum). Refers to human CarnegieStage10. synonym: "E8-9.25" EXACT [] synonym: "TS13" EXACT [] synonym: "TS13 (E8-9.25)" RELATED [EMAPA:TS13] xref: EMAPA:TS13 xref: XUO:0000057 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000019 ! Theiler stage 12 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker EMAPA:16441 property_value: has_stage_marker EMAPA:16445 property_value: has_stage_marker EMAPA:16449 property_value: start_dpc "8.5" xsd:float [Term] id: MmusDv:0000021 name: Theiler stage 14 namespace: mouse_developmental_stage def: "Organogenesis stage during which the rostral extremity of the neural tube closes in embryos with usually about 15-18 somite pairs. Late in the stage the 3rd branchial arch becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_14] comment: Embryonic age 9 dpc (day post coitum). Refers to human CarnegieStage11. synonym: "E8.5-9.75" EXACT [] synonym: "TS14" EXACT [] synonym: "TS14 (E8.5-9.75)" RELATED [EMAPA:TS14] xref: EMAPA:TS14 xref: XUO:0000058 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000020 ! Theiler stage 13 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker EMAPA:16445 property_value: has_stage_marker EMAPA:16449 property_value: has_stage_marker EMAPA:16453 property_value: has_stage_marker EMAPA:16457 property_value: start_dpc "9.0" xsd:float [Term] id: MmusDv:0000022 name: Theiler stage 15 namespace: mouse_developmental_stage def: "Organogenesis stage during which the posterior neuropore forms and the condensation of the forelimb bud becomes apparent near the 8th-12th somite pairs." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_15] comment: Embryonic age 9.5 dpc (day post coitum). Refers to human CarnegieStage12. synonym: "E9-10.25" EXACT [] synonym: "TS15" EXACT [] synonym: "TS15 (E9-10.25)" RELATED [EMAPA:TS15] xref: EMAPA:TS15 xref: XUO:0000059 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000021 ! Theiler stage 14 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker UBERON:0005417 property_value: start_dpc "9.5" xsd:float [Term] id: MmusDv:0000023 name: Theiler stage 16 namespace: mouse_developmental_stage def: "Organogenesis stage during which the posterior neuropore closes and the hind limb bud becomes visible at the level of the 23rd-28th somites." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_16] comment: Embryonic age 10 dpc (day post coitum). Refers to human CarnegieStages 13 to 15. synonym: "E9.5-10.75" EXACT [] synonym: "TS16" EXACT [] synonym: "TS16 (E9.5-10.75)" RELATED [EMAPA:TS16] xref: EMAPA:TS16 xref: XUO:0000060 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000022 ! Theiler stage 15 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker UBERON:0005418 property_value: start_dpc "10.0" xsd:float [Term] id: MmusDv:0000024 name: Theiler stage 17 namespace: mouse_developmental_stage def: "Organogenesis stage defined by the deepening of the lens pit and the first appearance of the physiological umbilical hernia." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_17] comment: Embryonic age 10.5 dpc (day post coitum). Refers to human CarnegieStages 13 to 15. synonym: "E10-11.25" EXACT [] synonym: "TS17" EXACT [] synonym: "TS17 (E10-11.25)" RELATED [EMAPA:TS17] xref: EMAPA:TS17 xref: XUO:0000061 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000023 ! Theiler stage 16 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker EMAPA:18411 property_value: has_stage_marker UBERON:0006259 property_value: start_dpc "10.5" xsd:float [Term] id: MmusDv:0000025 name: Theiler stage 18 namespace: mouse_developmental_stage def: "Organogenesis stage during which the lens vesicle gradually closes and the nasal pits start to form. The rapid growth of the brain is striking." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_18] comment: Embryonic age 11 dpc (day post coitum). Refers to human CarnegieStages 13 to 15. synonym: "E10.5-11.25" EXACT [] synonym: "TS18" EXACT [] synonym: "TS18 (E10.5-11.25)" RELATED [EMAPA:TS18] xref: EMAPA:TS18 xref: XUO:0000062 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000024 ! Theiler stage 17 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker UBERON:0005870 property_value: start_dpc "11.0" xsd:float [Term] id: MmusDv:0000026 name: Theiler stage 19 namespace: mouse_developmental_stage def: "Organogenesis stage during which the lens vesicle becomes completely closed and detached from the ectoderm, and peripheral margins of the eye become well defined." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_19] comment: Embryonic age 11.5 dpc (day post coitum). Refers to human CarnegieStage16. synonym: "E11-12.25" EXACT [] synonym: "TS19" EXACT [] synonym: "TS19 (E11-12.25)" RELATED [EMAPA:TS19] xref: EMAPA:TS19 xref: XUO:0000063 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000025 ! Theiler stage 18 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: start_dpc "11.5" xsd:float [Term] id: MmusDv:0000027 name: Theiler stage 20 namespace: mouse_developmental_stage def: "Organogenesis stage during which the handplate develops angles corresponding to the future digits, and tongue and brain vesicles are clearly visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_20] comment: Embryonic age 12 dpc (day post coitum). Refers to human CarnegieStage17. synonym: "E11.5-13" EXACT [] synonym: "TS20" EXACT [] synonym: "TS20 (E11.5-13)" RELATED [EMAPA:TS20] xref: EMAPA:TS20 xref: XUO:0000064 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000026 ! Theiler stage 19 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: start_dpc "12.0" xsd:float [Term] id: MmusDv:0000028 name: Theiler stage 21 namespace: mouse_developmental_stage def: "Organogenesis stage during which the digit widths and locations can be discerned, and the pinna rapidly develops and forms a crest at right angles to the head." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_21] comment: Embryonic age 13 dpc (day post coitum). Refers to human CarnegieStages 18 and 19. synonym: "E12.5-14" EXACT [] synonym: "TS21" EXACT [] synonym: "TS21 (E12.5-14)" RELATED [EMAPA:TS21] xref: EMAPA:TS21 xref: XUO:0000065 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000027 ! Theiler stage 20 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: start_dpc "13.0" xsd:float [Term] id: MmusDv:0000029 name: Theiler stage 22 namespace: mouse_developmental_stage def: "Organogenesis stage during which the fingers are clearly visible and the long bones of the limbs are present." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_22] comment: Embryonic age 14 dpc (day post coitum). Refers to human CarnegieStages 20 to 23. synonym: "E13.5-15" EXACT [] synonym: "TS22" EXACT [] synonym: "TS22 (E13.5-15)" RELATED [EMAPA:TS22] xref: EMAPA:TS22 xref: XUO:0000066 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000028 ! Theiler stage 21 relationship: part_of MmusDv:0000018 ! organogenesis stage property_value: has_stage_marker UBERON:0003606 property_value: start_dpc "14.0" xsd:float [Term] id: MmusDv:0000030 name: post-embryonic developmental stage namespace: mouse_developmental_stage def: "mouse life cycle that follows the embryonic development stage and during which further organogenesis and histogenesis occur." [Bgee:curator] comment: This term was obsoleted to follow human developmental ontology structure. is_obsolete: true [Term] id: MmusDv:0000031 name: fetal stage namespace: mouse_developmental_stage def: "Prenatal stage that starts with the fully formed embryo and ends at birth." [Bgee:curator] comment: This stage describes the four Theiler stages that are commonly reported as equivalent to the human fetal period in the literature. They are anyway defined by embryonic days. xref: UBERON:0007220 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000042 ! prenatal stage [Term] id: MmusDv:0000032 name: Theiler stage 23 namespace: mouse_developmental_stage def: "Fetal stage during which the toes separate and hair follicles are present in the cephalic region but not at the periphery of the vibrissae." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_23] comment: Embryonic age 15 dpc (day post coitum). Refers to the human fetal period. synonym: "E15" EXACT [] synonym: "TS23" EXACT [] synonym: "TS23 (E15)" RELATED [EMAPA:TS23] xref: EMAPA:TS23 xref: XUO:0000067 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000029 ! Theiler stage 22 relationship: part_of MmusDv:0000031 ! fetal stage property_value: start_dpc "15.0" xsd:float [Term] id: MmusDv:0000033 name: Theiler stage 24 namespace: mouse_developmental_stage def: "Fetal stage during which the umbilical hernia disappears and there is a corresponding increase in the size of the peritoneal sac." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_24] comment: Embryonic age 16 dpc (day post coitum). Refers to the human fetal period. synonym: "E16" EXACT [] synonym: "TS24" EXACT [] synonym: "TS24 (E16)" RELATED [EMAPA:TS24] xref: EMAPA:TS24 xref: XUO:0000068 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000032 ! Theiler stage 23 relationship: part_of MmusDv:0000031 ! fetal stage property_value: start_dpc "16.0" xsd:float [Term] id: MmusDv:0000034 name: Theiler stage 25 namespace: mouse_developmental_stage def: "Fetal stage during which the thickened skin forms wrinkles and the subcutaneous veins are less visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_25] comment: Embryonic age 17 dpc (day post coitum). Refers to the human fetal period. synonym: "E17" EXACT [] synonym: "TS25" EXACT [] synonym: "TS25 (E17)" RELATED [EMAPA:TS25] xref: EMAPA:TS25 xref: XUO:0000069 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000033 ! Theiler stage 24 relationship: part_of MmusDv:0000031 ! fetal stage property_value: start_dpc "17.0" xsd:float [Term] id: MmusDv:0000035 name: Theiler stage 26 namespace: mouse_developmental_stage def: "Fetal stage defined by long whiskers and during which the eyes are barely visible through the closed eyelids." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_26] comment: TS26 is used for the period from embryonic day 18 up to birth itself. [https://github.com/tfhayamizu] synonym: "E18" EXACT [] synonym: "TS26" EXACT [] synonym: "TS26 (E18)" RELATED [EMAPA:TS26] xref: EMAPA:TS26 xref: XUO:0000070 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000034 ! Theiler stage 25 relationship: part_of MmusDv:0000031 ! fetal stage property_value: end_wpb "0.0" xsd:float property_value: start_dpc "18.0" xsd:float [Term] id: MmusDv:0000036 name: Theiler stage 27 namespace: mouse_developmental_stage def: "Stage that refers to the newborn mouse, aged E19-20, P0. Description of anatomical structures related to this stage corresponds to the first days of the mouse life. Used for postnatal days 0 through 3." [https://github.com/tfhayamizu] comment: TS27 is used for postnatal days 0 through 3 (P0 to P3). This is a somewhat arbitrary cut-off but seems to best fit the data we have encountered. TS28 is then used from postnatal day 4 onward. [https://github.com/tfhayamizu] synonym: "P0" RELATED [UBERON:cjm] synonym: "TS27" RELATED [EMAPA:TS27] xref: EMAPA:TS27 xref: UBERON:0007221 xref: XUO:0000071 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000035 ! Theiler stage 26 relationship: part_of MmusDv:0000092 ! postpartum stage property_value: end_wpb "0.6" xsd:float property_value: EXACT%5B%5D "newborn stage" xsd:string {xref="UBERON:cjm"} property_value: start_dpc "19.0" xsd:float property_value: start_wpb "0.0" xsd:float [Term] id: MmusDv:0000037 name: Theiler stage 28 namespace: mouse_developmental_stage def: "Postnatal development that covers the period after the TS27 stage (P0-P3 first days of life) and continuing to adulthood. P4 to adulthood." [https://github.com/tfhayamizu] synonym: "TS28" RELATED [] xref: EMAPA:TS28 xref: XUO:0000072 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000036 ! Theiler stage 27 relationship: part_of MmusDv:0000092 ! postpartum stage property_value: start_wpb "0.6" xsd:float [Term] id: MmusDv:0000038 name: infant stage namespace: mouse_developmental_stage def: "Immature stage that refers to a mouse which is over 1 week and under 6 weeks old." [Bgee:curator] comment: This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad] synonym: "1-5 weeks" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000096 ! early immature stage relationship: part_of MmusDv:0000043 ! immature stage property_value: end_wpb "6.0" xsd:float property_value: start_wpb "1.0" xsd:float is_obsolete: true consider: MmusDv:0000112 [Term] id: MmusDv:0000039 name: adolescent stage namespace: mouse_developmental_stage def: "Immature stage that refers to a mouse which is over 4 weeks and under 7 weeks old." [Bgee:curator] comment: This term was obsoleted as it is not fully accepted as a defined developmental stage in the literature. This stage describes the age at which mice are usually used as adolescent mouse models in the literature. synonym: "4-6 weeks" EXACT [] is_obsolete: true [Term] id: MmusDv:0000040 name: adult stage namespace: mouse_developmental_stage def: "Mouse developmental stage that refers to a mouse which is over 5 weeks old." [Bgee:curator] comment: This term was obsoleted to include the mature stage into the ontology. Both terms have the same children, but contains of children (children of children) differ. The organisation of the postnatal development time in mouse is debatable, literature usually refers to mature or immature mice, with milestone around 6-8 weeks post-natal. synonym: "mature" EXACT [] is_obsolete: true replaced_by: MmusDv:0000110 [Term] id: MmusDv:0000041 name: unknown namespace: mouse_developmental_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000001 ! mouse life cycle [Term] id: MmusDv:0000042 name: prenatal stage namespace: mouse_developmental_stage def: "Mouse life cycle that starts with fertilization and ends with birth." [UBERON:0000068] xref: UBERON:0000068 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000001 ! mouse life cycle property_value: end_dpc "19.0" xsd:float property_value: end_ypb "0.0" xsd:float property_value: start_dpc "0.45" xsd:float property_value: start_dpf "0.0" xsd:float [Term] id: MmusDv:0000043 name: immature stage namespace: mouse_developmental_stage def: "Mouse developmental stage that covers the period from birth until 5 weeks old." [Bgee:curator] comment: This term was made obsolete and replaced by premature stage, starting at P4 instead of birth, due to TS28 definition. [ANiknejad] xref: EMAPA:TS28 xref: UBERON:0000112 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000092 ! postpartum stage property_value: end_wpb "6.0" xsd:float property_value: start_dpc "19.0" xsd:float property_value: start_wpb "0.0" xsd:float is_obsolete: true consider: MmusDv:0000112 [Term] id: MmusDv:0000044 name: 1-7 days namespace: mouse_developmental_stage def: "Early immature stage that refers to the newborn mouse which is over 1 and under 8 days old." [Bgee:curator] comment: This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000036 ! Theiler stage 27 relationship: part_of MmusDv:0000096 ! early immature stage property_value: end_wpb "1.143" xsd:float property_value: start_wpb "0.143" xsd:float is_obsolete: true consider: MmusDv:0000036 consider: MmusDv:0000112 consider: MmusDv:0000113 [Term] id: MmusDv:0000045 name: 1 week namespace: mouse_developmental_stage def: "Premature stage that refers to a mouse which is over 7 days and under 15 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000113 ! 4-7 days relationship: part_of MmusDv:0000112 ! premature stage property_value: end_wpb "2.0" xsd:float property_value: start_wpb "1.0" xsd:float [Term] id: MmusDv:0000046 name: 2 weeks namespace: mouse_developmental_stage def: "Premature stage that refers to a mouse which is over 14 days and under 22 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000045 ! 1 week relationship: part_of MmusDv:0000112 ! premature stage property_value: end_wpb "3.0" xsd:float property_value: start_wpb "2.0" xsd:float [Term] id: MmusDv:0000047 name: 3 weeks namespace: mouse_developmental_stage def: "Premature stage that refers to a mouse which is over 21 days and under 29 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000046 ! 2 weeks relationship: part_of MmusDv:0000112 ! premature stage property_value: end_wpb "4.0" xsd:float property_value: start_wpb "3.0" xsd:float [Term] id: MmusDv:0000048 name: 4 weeks namespace: mouse_developmental_stage def: "Premature stage that refers to a mouse which is over 28 days and under 36 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000047 ! 3 weeks relationship: part_of MmusDv:0000112 ! premature stage property_value: end_wpb "5.0" xsd:float property_value: start_wpb "4.0" xsd:float [Term] id: MmusDv:0000049 name: 5 weeks namespace: mouse_developmental_stage def: "Premature stage that refers to a mouse which is over 35 days and under 43 days old." [Bgee:curator] comment: This stage is usually the stage during which the sexual maturity occurs. is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000048 ! 4 weeks relationship: part_of MmusDv:0000112 ! premature stage property_value: end_wpb "6.0" xsd:float property_value: start_wpb "5.0" xsd:float [Term] id: MmusDv:0000050 name: 6 weeks namespace: mouse_developmental_stage def: "Early stage that refers to a mouse which is over 42 days and under 50 days old." [Bgee:curator] comment: This stage is commonly considered in the literature as the milestone that distinguishes between sexually immmature and mature stages (see http://www.ahc.umn.edu/rar/breeding.html). is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000049 ! 5 weeks relationship: part_of MmusDv:0000061 ! early adult stage property_value: end_wpb "7.0" xsd:float property_value: start_wpb "6.0" xsd:float [Term] id: MmusDv:0000051 name: 7 weeks namespace: mouse_developmental_stage def: "Early adult stage that refers to a mouse which is over 49 days and under 57 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000050 ! 6 weeks relationship: part_of MmusDv:0000061 ! early adult stage property_value: end_wpb "8.0" xsd:float property_value: start_wpb "7.0" xsd:float [Term] id: MmusDv:0000052 name: 8 weeks namespace: mouse_developmental_stage def: "2 month-old stage that refers to a mouse which is over 56 days and under 64 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000051 ! 7 weeks relationship: part_of MmusDv:0000062 ! 2 month-old stage property_value: end_wpb "9.0" xsd:float property_value: start_wpb "8.0" xsd:float [Term] id: MmusDv:0000053 name: 9 weeks namespace: mouse_developmental_stage def: "2 month-old stage that refers to a mouse which is over 63 days and under 71 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000052 ! 8 weeks relationship: part_of MmusDv:0000062 ! 2 month-old stage property_value: end_wpb "10.0" xsd:float property_value: start_wpb "9.0" xsd:float [Term] id: MmusDv:0000054 name: 10 weeks namespace: mouse_developmental_stage def: "2 month-old stage that refers to a mouse which is over 70 days and under 78 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000053 ! 9 weeks relationship: part_of MmusDv:0000062 ! 2 month-old stage property_value: end_wpb "11.0" xsd:float property_value: start_wpb "10.0" xsd:float [Term] id: MmusDv:0000055 name: 11 weeks namespace: mouse_developmental_stage def: "2 month-old stage that refers to a mouse which is over 77 days and under 85 days old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000054 ! 10 weeks relationship: part_of MmusDv:0000062 ! 2 month-old stage property_value: end_wpb "12.0" xsd:float property_value: start_wpb "11.0" xsd:float [Term] id: MmusDv:0000056 name: 12 weeks namespace: mouse_developmental_stage def: "3 month-old stage that refers to a mouse which is over 84 days and under 92 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000055 ! 11 weeks relationship: part_of MmusDv:0000063 ! 3 month-old stage property_value: end_wpb "13.0" xsd:float property_value: start_wpb "12.0" xsd:float [Term] id: MmusDv:0000057 name: 13 weeks namespace: mouse_developmental_stage def: "3 month-old stage that refers to a mouse which is over 91 days and under 99 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000056 ! 12 weeks relationship: part_of MmusDv:0000063 ! 3 month-old stage property_value: end_wpb "14.0" xsd:float property_value: start_wpb "13.0" xsd:float [Term] id: MmusDv:0000058 name: 14 weeks namespace: mouse_developmental_stage def: "3 month-old stage that refers to a mouse which is over 98 days and under 106 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000057 ! 13 weeks relationship: part_of MmusDv:0000063 ! 3 month-old stage property_value: end_wpb "15.0" xsd:float property_value: start_wpb "14.0" xsd:float [Term] id: MmusDv:0000059 name: 15 weeks namespace: mouse_developmental_stage def: "3 month-old stage that refers to a mouse which is over 105 days and under 113 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000058 ! 14 weeks relationship: part_of MmusDv:0000063 ! 3 month-old stage property_value: end_wpb "16.0" xsd:float property_value: start_wpb "15.0" xsd:float [Term] id: MmusDv:0000061 name: early adult stage namespace: mouse_developmental_stage def: "Mature stage that refers to a adult mouse which is over 6 weeks and under 7 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD] comment: Mice under 7 months of age are commonly considered as young adult in the literature, without loss of functional capability like hearing (see http://www.ncbi.nlm.nih.gov/pubmed/18259074). xref: UBERON:0018241 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000110 ! mature stage property_value: end_mpb "7.0" xsd:float property_value: end_wpb "30.0" xsd:float property_value: start_mpb "1.5" xsd:float property_value: start_wpb "6.0" xsd:float [Term] id: MmusDv:0000062 name: 2 month-old stage namespace: mouse_developmental_stage def: "Early adult stage that refers to a mouse which is over 2 and under 3 months old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000051 ! 7 weeks relationship: part_of MmusDv:0000061 ! early adult stage property_value: end_mpb "3.0" xsd:float property_value: end_wpb "12.0" xsd:float property_value: start_mpb "2.0" xsd:float property_value: start_wpb "8.0" xsd:float [Term] id: MmusDv:0000063 name: 3 month-old stage namespace: mouse_developmental_stage def: "Early adult stage that refers to a mouse which is over 3 and under 4 months old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000062 ! 2 month-old stage relationship: part_of MmusDv:0000061 ! early adult stage property_value: end_mpb "4.0" xsd:float property_value: end_wpb "16.0" xsd:float property_value: start_mpb "3.0" xsd:float property_value: start_wpb "12.0" xsd:float [Term] id: MmusDv:0000064 name: 4 month-old stage namespace: mouse_developmental_stage def: "Early adult stage that refers to a mouse which is over 4 and under 5 months old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000063 ! 3 month-old stage relationship: part_of MmusDv:0000061 ! early adult stage property_value: end_mpb "5.0" xsd:float property_value: end_wpb "21.0" xsd:float property_value: start_mpb "4.0" xsd:float property_value: start_wpb "16.0" xsd:float [Term] id: MmusDv:0000065 name: 16 weeks namespace: mouse_developmental_stage def: "4 month-old stage that refers to a mouse which is over 112 days and under 120 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000059 ! 15 weeks relationship: part_of MmusDv:0000064 ! 4 month-old stage property_value: end_wpb "17.0" xsd:float property_value: start_wpb "16.0" xsd:float [Term] id: MmusDv:0000066 name: 17 weeks namespace: mouse_developmental_stage def: "4 month-old stage that refers to a mouse which is over 119 days and under 127 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000065 ! 16 weeks relationship: part_of MmusDv:0000064 ! 4 month-old stage property_value: end_wpb "18.0" xsd:float property_value: start_wpb "17.0" xsd:float [Term] id: MmusDv:0000067 name: 18 weeks namespace: mouse_developmental_stage def: "4 month-old stage that refers to a mouse which is over 126 days and under 134 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000066 ! 17 weeks relationship: part_of MmusDv:0000064 ! 4 month-old stage property_value: end_wpb "19.0" xsd:float property_value: start_wpb "18.0" xsd:float [Term] id: MmusDv:0000068 name: 19 weeks namespace: mouse_developmental_stage def: "4 month-old stage that refers to a mouse which is over 133 days and under 141 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000067 ! 18 weeks relationship: part_of MmusDv:0000064 ! 4 month-old stage property_value: end_wpb "20.0" xsd:float property_value: start_wpb "19.0" xsd:float [Term] id: MmusDv:0000069 name: 5 month-old stage namespace: mouse_developmental_stage def: "Early adult stage that refers to a mouse which is over 5 and under 6 months old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000064 ! 4 month-old stage relationship: part_of MmusDv:0000061 ! early adult stage property_value: end_mpb "6.0" xsd:float property_value: end_wpb "25.0" xsd:float property_value: start_mpb "5.0" xsd:float property_value: start_wpb "21.0" xsd:float [Term] id: MmusDv:0000070 name: 20 weeks namespace: mouse_developmental_stage def: "4 month-old stage that refers to a mouse which is over 140 days and under 148 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000068 ! 19 weeks relationship: part_of MmusDv:0000064 ! 4 month-old stage property_value: end_wpb "21.0" xsd:float property_value: start_wpb "20.0" xsd:float [Term] id: MmusDv:0000071 name: 21 weeks namespace: mouse_developmental_stage def: "5 month-old stage that refers to a mouse which is over 147 days and under 155 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000070 ! 20 weeks relationship: part_of MmusDv:0000069 ! 5 month-old stage property_value: end_wpb "22.0" xsd:float property_value: start_wpb "21.0" xsd:float [Term] id: MmusDv:0000072 name: 22 weeks namespace: mouse_developmental_stage def: "5 month-old stage that refers to a mouse which is over 154 days and under 162 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000071 ! 21 weeks relationship: part_of MmusDv:0000069 ! 5 month-old stage property_value: end_wpb "23.0" xsd:float property_value: start_wpb "22.0" xsd:float [Term] id: MmusDv:0000073 name: 23 weeks namespace: mouse_developmental_stage def: "5 month-old stage that refers to a mouse which is over 161 days and under 169 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000072 ! 22 weeks relationship: part_of MmusDv:0000069 ! 5 month-old stage property_value: end_wpb "24.0" xsd:float property_value: start_wpb "23.0" xsd:float [Term] id: MmusDv:0000074 name: 24 weeks namespace: mouse_developmental_stage def: "5 month-old stage that refers to a mouse which is over 168 days and under 176 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000073 ! 23 weeks relationship: part_of MmusDv:0000069 ! 5 month-old stage property_value: end_wpb "25.0" xsd:float property_value: start_wpb "24.0" xsd:float [Term] id: MmusDv:0000075 name: middle aged stage namespace: mouse_developmental_stage def: "Late adult stage that refers to a mouse which is over 7 and under 15 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD] comment: This stage is commonly considered in the literature as the stage during which first evidence of loss of functional capability like hearing occurs in wild type mouse strain (see http://www.ncbi.nlm.nih.gov/pubmed/18259074). is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000097 ! late adult stage property_value: end_mpb "15.0" xsd:float property_value: start_mpb "7.0" xsd:float property_value: start_wpb "30.0" xsd:float [Term] id: MmusDv:0000076 name: aged adult stage namespace: mouse_developmental_stage def: "Late adult stage that refers to a mouse which is over 15 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000075 ! middle aged stage relationship: part_of MmusDv:0000097 ! late adult stage property_value: start_mpb "15.0" xsd:float [Term] id: MmusDv:0000077 name: 6 month-old stage namespace: mouse_developmental_stage def: "Early adult stage that refers to a mouse which is over 6 and under 7 months old." [Bgee:curator] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000069 ! 5 month-old stage relationship: part_of MmusDv:0000061 ! early adult stage property_value: end_mpb "7.0" xsd:float property_value: end_wpb "30.0" xsd:float property_value: start_mpb "6.0" xsd:float property_value: start_wpb "25.0" xsd:float [Term] id: MmusDv:0000078 name: 7 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 7 and under 8 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000077 ! 6 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "8.0" xsd:float property_value: start_mpb "7.0" xsd:float property_value: start_wpb "30.0" xsd:float [Term] id: MmusDv:0000079 name: 8 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 8 and under 9 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000078 ! 7 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "9.0" xsd:float property_value: start_mpb "8.0" xsd:float [Term] id: MmusDv:0000080 name: 9 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 9 and under 10 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000079 ! 8 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "10.0" xsd:float property_value: start_mpb "9.0" xsd:float [Term] id: MmusDv:0000081 name: 10 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 10 and under 11 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000080 ! 9 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "11.0" xsd:float property_value: start_mpb "10.0" xsd:float [Term] id: MmusDv:0000082 name: 11 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 11 and under 12 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000081 ! 10 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "12.0" xsd:float property_value: start_mpb "11.0" xsd:float [Term] id: MmusDv:0000083 name: 12 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 12 and under 13 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000082 ! 11 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "13.0" xsd:float property_value: start_mpb "12.0" xsd:float [Term] id: MmusDv:0000084 name: 13 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 13 and under 14 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000083 ! 12 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "14.0" xsd:float property_value: start_mpb "13.0" xsd:float [Term] id: MmusDv:0000085 name: 14 month-old stage namespace: mouse_developmental_stage def: "Middle aged stage that refers to a mouse which is over 14 and under 15 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000084 ! 13 month-old stage relationship: part_of MmusDv:0000075 ! middle aged stage property_value: end_mpb "15.0" xsd:float property_value: start_mpb "14.0" xsd:float [Term] id: MmusDv:0000086 name: 15 month-old stage namespace: mouse_developmental_stage def: "Aged adult stage that refers to a mouse which is over 15 and under 16 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000085 ! 14 month-old stage relationship: part_of MmusDv:0000076 ! aged adult stage property_value: end_mpb "16.0" xsd:float property_value: start_mpb "15.0" xsd:float [Term] id: MmusDv:0000087 name: 16 month-old stage namespace: mouse_developmental_stage def: "Aged adult stage that refers to a mouse which is over 16 and under 17 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000086 ! 15 month-old stage relationship: part_of MmusDv:0000076 ! aged adult stage property_value: end_mpb "17.0" xsd:float property_value: start_mpb "16.0" xsd:float [Term] id: MmusDv:0000088 name: 17 month-old stage namespace: mouse_developmental_stage def: "Aged adult stage that refers to a mouse which is over 17 and under 18 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000087 ! 16 month-old stage relationship: part_of MmusDv:0000076 ! aged adult stage property_value: end_mpb "18.0" xsd:float property_value: start_mpb "17.0" xsd:float [Term] id: MmusDv:0000089 name: 18 month-old stage namespace: mouse_developmental_stage def: "Aged adult stage that refers to a mouse which is over 18 and under 19 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000088 ! 17 month-old stage relationship: part_of MmusDv:0000076 ! aged adult stage property_value: end_mpb "19.0" xsd:float property_value: start_mpb "18.0" xsd:float [Term] id: MmusDv:0000090 name: 19 month-old stage namespace: mouse_developmental_stage def: "Aged adult stage that refers to a mouse which is over 19 and under 20 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000089 ! 18 month-old stage relationship: part_of MmusDv:0000076 ! aged adult stage property_value: end_mpb "20.0" xsd:float property_value: start_mpb "19.0" xsd:float [Term] id: MmusDv:0000091 name: 20 month-old stage and over namespace: mouse_developmental_stage def: "Aged adult stage that refers to a mouse which is over 20 months old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000090 ! 19 month-old stage relationship: part_of MmusDv:0000076 ! aged adult stage property_value: start_mpb "20.0" xsd:float [Term] id: MmusDv:0000092 name: postpartum stage namespace: mouse_developmental_stage def: "Mouse developmental stage that covers the period from birth until late adulthood." [Bgee:curator] xref: UBERON:0000066 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000042 ! prenatal stage relationship: part_of MmusDv:0000001 ! mouse life cycle property_value: start_dpc "19.0" xsd:float property_value: start_wpb "0.0" xsd:float [Term] id: MmusDv:0000093 name: Theiler stage 11b namespace: mouse_developmental_stage def: "Embryonic neurula stage during which the neural plate formation occurs and the allantoic bud elongates ." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11] synonym: "TS11b" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000111 ! Theiler stage 11a relationship: part_of MmusDv:0000017 ! Theiler stage 11 [Term] id: MmusDv:0000094 name: Theiler stage 11c namespace: mouse_developmental_stage def: "Embryonic neurula stage during which the neural plate formation occurs and the head folds are formed while the neural groove becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11] synonym: "TS11c" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000093 ! Theiler stage 11b relationship: part_of MmusDv:0000017 ! Theiler stage 11 [Term] id: MmusDv:0000095 name: Theiler stage 11d namespace: mouse_developmental_stage def: "Embryonic neurula stage during which the neural plate formation occurs and the head folds continue to enlarge while the foregut pocket begins to form." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11] synonym: "TS11d" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000094 ! Theiler stage 11c relationship: part_of MmusDv:0000017 ! Theiler stage 11 [Term] id: MmusDv:0000096 name: early immature stage namespace: mouse_developmental_stage def: "Immature stage that covers the period from birth until end of the first week." [Bgee:curator] comment: This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad] xref: UBERON:0007221 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000043 ! immature stage property_value: end_wpb "1.0" xsd:float property_value: start_dpc "19.0" xsd:float property_value: start_wpb "0.0" xsd:float is_obsolete: true consider: MmusDv:0000036 consider: MmusDv:0000112 [Term] id: MmusDv:0000097 name: late adult stage namespace: mouse_developmental_stage def: "Mature stage that refers to an adult mouse which is over 7 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD] xref: UBERON:0007222 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000110 ! mature stage property_value: start_mpb "7.0" xsd:float property_value: start_wpb "30.0" xsd:float [Term] id: MmusDv:0000098 name: 25 weeks namespace: mouse_developmental_stage def: "6 month-old stage that refers to a mouse which is over 175 days and under 183 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000074 ! 24 weeks relationship: part_of MmusDv:0000077 ! 6 month-old stage property_value: end_wpb "26.0" xsd:float property_value: start_wpb "25.0" xsd:float [Term] id: MmusDv:0000099 name: 26 weeks namespace: mouse_developmental_stage def: "6 month-old stage that refers to a mouse which is over 182 days and under 190 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000098 ! 25 weeks relationship: part_of MmusDv:0000077 ! 6 month-old stage property_value: end_wpb "27.0" xsd:float property_value: start_wpb "26.0" xsd:float [Term] id: MmusDv:0000100 name: 27 weeks namespace: mouse_developmental_stage def: "6 month-old stage that refers to a mouse which is over 189 days and under 197 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000099 ! 26 weeks relationship: part_of MmusDv:0000077 ! 6 month-old stage property_value: end_wpb "28.0" xsd:float property_value: start_wpb "27.0" xsd:float [Term] id: MmusDv:0000101 name: 28 weeks namespace: mouse_developmental_stage def: "6 month-old stage that refers to a mouse which is over 196 days and under 204 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000100 ! 27 weeks relationship: part_of MmusDv:0000077 ! 6 month-old stage property_value: end_wpb "29.0" xsd:float property_value: start_wpb "28.0" xsd:float [Term] id: MmusDv:0000102 name: 29 weeks namespace: mouse_developmental_stage def: "6 month-old stage that refers to a mouse which is over 203 days and under 211 days old." [Bgee:curator] subset: granular_stage is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000101 ! 28 weeks relationship: part_of MmusDv:0000077 ! 6 month-old stage property_value: end_wpb "30.0" xsd:float property_value: start_wpb "29.0" xsd:float [Term] id: MmusDv:0000103 name: Theiler stage 09a namespace: mouse_developmental_stage def: "Theiler developmental stage 9 defined by advanced endometrial reaction and during which the egg-cylinder stage advances with the first evidence of an embryonic axis." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_9a] synonym: "Theiler stage 9" EXACT [] synonym: "TS09a" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000014 ! Theiler stage 09 [Term] id: MmusDv:0000104 name: Theiler stage 09b namespace: mouse_developmental_stage def: "Theiler developmental stage 9 defined by advanced endometrial reaction and during which the first mesodermal cells are produced by gastrulation late in this stage." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_9b] synonym: "Theiler stage 9" EXACT [] synonym: "TS09b" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000103 ! Theiler stage 09a relationship: part_of MmusDv:0000014 ! Theiler stage 09 [Term] id: MmusDv:0000105 name: Theiler stage 10a namespace: mouse_developmental_stage def: "Theiler developmental stage 10 during which the tissue at the posterior end of the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_10a] comment: Refers to MS (mid-streak) stage in Downs and Davies staging of gastrulating mouse embryos (PMID: 8269852, 1993). synonym: "TS10a" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000015 ! Theiler stage 10 [Term] id: MmusDv:0000106 name: Theiler stage 10b namespace: mouse_developmental_stage def: "Theiler developmental stage 10 during which small cavities coalesce to form a single cavity in the mesoderm of the posterior amniotic fold, the exocoelom." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10b] comment: Refers to MS-LS (mid-streak to late streak) stage in Downs and Davies staging of gastrulating mouse embryos, 1993 (see http://www.ncbi.nlm.nih.gov/pubmed/8269852). synonym: "TS10b" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000105 ! Theiler stage 10a relationship: part_of MmusDv:0000015 ! Theiler stage 10 [Term] id: MmusDv:0000107 name: Theiler stage 10c namespace: mouse_developmental_stage def: "Theiler developmental stage 10 during which the allantoic bud first appears, gastrulation continues and the node becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10c] comment: Refers to MS-LS (mid-streak to late streak) stage in Downs and Davies staging of gastrulating mouse embryos, 1993 (see http://www.ncbi.nlm.nih.gov/pubmed/8269852). synonym: "TS10c" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000106 ! Theiler stage 10b relationship: part_of MmusDv:0000015 ! Theiler stage 10 [Term] id: MmusDv:0000108 name: Theiler stage 12a namespace: mouse_developmental_stage def: "Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 1-4 and during which the allantois extends further into the exocoelom. Maxillary components of the 1st branchial arch become prominent. The preotic sulcus is visible in the 2-3 somite embryo. The cardiogenic plate begins to form and the foregut pocket is clearly visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12a] comment: Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09. synonym: "TS12a" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000019 ! Theiler stage 12 [Term] id: MmusDv:0000109 name: Theiler stage 12b namespace: mouse_developmental_stage def: "Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 5-7 and during which neural closure occurs in the region of the 4th and 5th somites, extending in both directions from this site. Headfolds are particularly prominent. Optic placodes are first evident and become indented to form the optic pits. The heart rudiment develops rapidly. The allantois contacts the chorion at the end of this stage." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12b] comment: Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09. synonym: "TS12b" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000108 ! Theiler stage 12a relationship: part_of MmusDv:0000019 ! Theiler stage 12 [Term] id: MmusDv:0000110 name: mature stage namespace: mouse_developmental_stage def: "Mouse developmental stage that refers to a sexually mature adult mouse which is over 6 weeks old." [Bgee:curator] synonym: "mature" EXACT [] xref: UBERON:0000113 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000112 ! premature stage relationship: part_of MmusDv:0000037 ! Theiler stage 28 property_value: start_mpb "1.5" xsd:float property_value: start_wpb "6.0" xsd:float [Term] id: MmusDv:0000111 name: Theiler stage 11a namespace: mouse_developmental_stage def: "Embryonic neurula stage during which the neural plate formation occurs and the amniotic cavity is sealed off into three distinct cavities - the amniotic cavity, the exocoelom and the ectoplacental cleft." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11] synonym: "TS11a" EXACT [] is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000017 ! Theiler stage 11 [Term] id: MmusDv:0000112 name: premature stage namespace: mouse_developmental_stage def: "Mouse developmental stage that covers the period from P4 starting at TS28 until 5 weeks old." [Bgee:curator] comment: It is commonly accepted that mouse reaches sexual maturity by six weeks of age (see http://www.ahc.umn.edu/rar/breeding.html). We start this stage at P4 because TS27 'newborn' stage is not defined as a postnatal stage. synonym: "infant stage" RELATED [] xref: EMAPA:TS28 xref: UBERON:0000112 is_a: MmusDv:0000000 ! mouse life cycle stage relationship: part_of MmusDv:0000037 ! Theiler stage 28 property_value: end_wpb "6.0" xsd:float property_value: start_wpb "0.6" xsd:float [Term] id: MmusDv:0000113 name: 4-7 days namespace: mouse_developmental_stage def: "Premature stage that refers to the newborn mouse which is over 4 days and under 8 days old." [Bgee:curator] comment: This stage starts at P4. is_a: MmusDv:0000000 ! mouse life cycle stage relationship: immediately_preceded_by MmusDv:0000036 ! Theiler stage 27 relationship: part_of MmusDv:0000112 ! premature stage property_value: end_wpb "1.0" xsd:float property_value: start_wpb "0.6" xsd:float [Typedef] id: end_dpc name: end, days post coitum def: "Count of number of days intervening between the end of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy] comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. property_value: has_unit UO:0000033 is_metadata_tag: true [Typedef] id: end_mpb name: end, months post birth def: "Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the mouse is one month old has the value 2" [] comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. property_value: has_unit UO:0000035 is_metadata_tag: true [Typedef] id: end_wpb name: end, weeks post birth def: "Count of number of weeks intervening between the end of the stage and the time of birth according to a reference model. Note that the first week of post-birth development has the value of 1 for this property, and the period during which the mouse is one week old has the value 2" [] comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. property_value: has_unit UO:0000034 is_metadata_tag: true [Typedef] id: has_end_time name: has end time is_metadata_tag: true [Typedef] id: has_start_time name: has start time is_metadata_tag: true [Typedef] id: has_unit name: has unit comment: Used to associate a measurement property (e.g. days post fertilization) with a unit (e.g. days) is_metadata_tag: true [Typedef] id: immediately_preceded_by name: immediately_preceded_by def: "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" [] xref: RO:0002087 is_a: preceded_by ! preceded_by [Typedef] id: part_of name: part of xref: BFO:0000050 is_transitive: true [Typedef] id: preceded_by name: preceded_by def: "X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X)" [] xref: BFO:0000062 is_transitive: true [Typedef] id: start_dpc name: start, days post coitum def: "Count of number of days intervening between the start of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy] comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. property_value: has_unit UO:0000033 is_metadata_tag: true [Typedef] id: start_dpf name: start, days post fertilization def: "Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property." [] comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. property_value: has_unit UO:0000033 is_metadata_tag: true [Typedef] id: start_mpb name: start, months post birth def: "Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the mouse is one month old has the value 1." [] comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. property_value: has_unit UO:0000035 is_metadata_tag: true [Typedef] id: start_wpb name: start, weeks post birth def: "Count of number of weeks intervening between the start of the stage and the time of birth according to a reference model. Note that the first week of post-birth development has the value of 0 for this property, and the period during which the mouse is one week old has the value 1." [] comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. property_value: has_unit UO:0000034 is_metadata_tag: true